Appendicitis


  • inflammation of the vermiform appendix
  • example of acute inflammation but may turn chronic
  • arises from blockage of appendix
    • faecoliths
    • food residues
    • lymphoid hyperplasia
    • diverticulosis of appendix
    • carcinoid tumour
  • or specific infection
    • Yersinia
    • Pseudomonas
    • Typhoid
    • Tuberculosis
    • Actinomycetes
  • or Inflammatory Bowel Disease

Symptoms and signs

  • Central abdominal pain, cramping or colicky
  • Nausea
  • Vomiting uncommon
  • ?Loose stool
  • After ~8 hours pain localises to RIF & becomes sharp/stabbing
    • made worse by coughing/moving
  • Pyrexia
  • Flushed
  • Fetor
  • White furred tongue
  • tachycardia
  • tender with guarding in McBurneys' point
  • PR tender anteriorly if peritonitis developing
  • Inflamed appendix stuck to bladder may cause frequency and pyuria

Investigations

  • FBC
    • WCC - >10x10^9 (but may not necessarily be raised)
  • USS
    •  mass or abscess not useful in early appendicitis
  • MSU
    • excludes UTI
  • b-HCG
    • to exclude ectopic pregnancy

Differential Diagnosis

Classical presentation

Non-classical

Treatment

  • NBM
  • appendicectomy
    • prophylactic metronidazole 1g PR 1 hour before
  • fluids
  • analgesia
  • AXR
  • DVT prophylaxis
    • heparin / clexane
  • Post-operatively
    • uncomplicated gets two doses antibiotics
    • perforated keep on antibiotics for 5 days

Complications

  • Perforation leading to generalised peritonitis
  • Appendix mass
  • Appendix abscess
  • pelvic abscess
  • sub-phrenic abscess
  • paralytic ilieus
  • septicaemia
  • portal pyaemia
  • tubal adhesions  - leading to infertility

 


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