Kernicterus


  • due to severe jaundice in neonatal period

  • bile pigment deposition in basal ganglia

  • results in brain damage, choreoathetosis and spasticity

  • mild cases can lead to deafness

Investigations

  • bilirubin <250mmol/l

Treatment

  • phototherapy

    • converts bilirubin to water soluble biliverdin

  • exchange tranfusion

 

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