Kaposis Sarcoma

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Kaposis Sarcoma


  • Tumour of vascular and lymphatic endothelium
  • associated with Human Herpesvirus-8 (HHV8)

Forms

  • classic / sporadic
    • elderly males (esp. Eastern European Jews)
    • slow growing purple tumours on foot / lower leg
    • rarely causes a problem
  • endemic
    • males from central Africa
    • more widespread cutaneous involvement
    • lymph node / systemic spread
    • oedema
  • immunosupression
    • HIV infection
    • widespread lesions
      • skin
      • bowel
      • oral cavity
      • lungs

Examination

  • purplish nodules / plaques

Treatment

  • radiotherapy
  • immunotherapy
  • cheomtherapy
 

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