Pyoderma Gangrenosum

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• unknown aetiology

Description

• erythematous nodules / pustules
• can be large and grow very quickly
• frequently ulcerated

Ulcer

• edge
  • bluish black
  • undermined
• surface
  • purulent

Associated Symptoms

• pyrexia
• malaise

Pathology

• intense neutrophilic infiltrate
• occasional vasculitis

Associations

• Inflammatory Bowel Disease
• Rheumatoid arthritis
• Multiple Myeloma
• Monoclonal Gammopathy
• Acute Leukaemias
• Lymphoma
• Liver disease
  • Primary Biliary Cirrhosis
  • Autoimmune Hepatitis
• Polycythaemia Rubra Vera
• Idiopathic

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