Hyperphosphataemia
- Increased phosphate leads to decreased 1-alpha hydroxylation of vitamin D
in kidney
- increased phosphate with calcium can result in calcium deposition in
tissues
Causes
- Renal failure
- hypoparathyroidism
- pseudohypoparathyroidism
- acromegaly
- excessive phosphate intake/administration
- Vitamin D intoxication
- Catabolic states
Treatment
- underlying cause
- aluminium or magnesium salts bind phosphate in gut and prevent absorption
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