Red cell abnormalities


Spherocytes

Fragmentation

  • DIC

  • macroangiopathy

  • HUS

  • TTP

  • burns

  • cardiac valves

Elliptocyte

  • hereditary elliptocyotsis

Tear drop / poikilocyte

  • myelofibrosis

  • extramedullary haemopoeisis

macrocyte

  • liver disease

  • alcoholism

  • megaloblastic anaemia

target cells

  • iron deficiency

  • liver disease

  • haemoglobinopathies

  • post-splenectomy

stomatocyte

  • liver disease

  • alcoholism

pencil cell

  • iron deficiency

Ecchinocyte

  • liver disease

  • post-splenectomy

Accanthocyte

  • liver disease

  • abetalipoproteinaemia

  • renal failure

sickle cell

  • sickle cell anaemia

microcyte

  • iron deficiency

  • haemoglobinopathy

Basket cell

  • oxidant damage

  • G6PD deficiency

  • unstable haemoglobin

Howell-Jolly body

  • hyposplenism

  • post-splenectomy

Basophilic stippling

  • haemoglobinopathy

  • lead poisoning

  • myelodysplasia

  • haemolytic anaemia

Malarial parasite

Siderotic granules / Pappenhemier bodies

  • sideroblastic anaemia

  • post-splenectomy

 

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