FSH
In males
- Stimulates Sertoli cells to produce inhibin (negative feedback effect)
- Stimulates Spermatogenesis
In Females
- Stimulates Granulosa cells to produce oestrogen
- along with LH promotes development of ovarian
follicle in females
Disorders
- Hyposecretion
- Hypersecretion
- premature sexual development in children
14.2.3.5 LH = luteinising hormone; FSH = follicle-stimulating hormone (from
gonadotroph cells)
| actions on ovary in female; on testis in male |
|
| control: via pulses of hypothalamic GnRH; feedback of
gonadal hormones |
|
| dysfunctions: hypogonadism, precocious puberty,
infertility. |
|
|