Luteinising Hormone


(LH)

  • In Testis:
    •  induces Leydig cells to produce testosterone
  • In Ovaries:
    • a surge of LH (in co-op. with FSH) at midcycle induces ovulation
    • maintains the corpus luteum after ovulation
    • induces luteal cells to produce progesterone
  • Control of release is via hypothalamic GnRH (pulsatile), and modulated by feedback loops involving the ovarian or testicular steroids

14.2.3.5 LH = luteinising hormone; FSH = follicle-stimulating hormone (from gonadotroph cells)

actions on ovary in female; on testis in male
control: via pulses of hypothalamic GnRH; feedback of gonadal hormones
dysfunctions: hypogonadism, precocious puberty, infertility.

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