Secretin

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  • released from duodenum and upper jejunum when stimulated by presence of acid
  • causes extralobular secretion of bicarbonate rich aqueous component of pancreatic juice
  • inhibits gastrin secretion by G cells
  • decreases response of parietal cells to secretagogues (acetylcholine, gastrin, histamine, etc.)
  • stimulates chief cells to produce pepsinogen

14.6.3 Secretin

produced from duodenum to ileum
actions: stimulation of HCO3 secretion from pancreas and liver
stimuli for secretion: acid in duodenum
 

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