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Haemochromatosis
hereditary haemochromatosis, bronze diabetes
- Hereditary defect of iron metabolism
- Autosomal recessive
- excessive iron absorption
- up to 10x normal
- leads to iron accumulation
- damage thought to be due to reactive oxygen species produced during normal
metabolism of O2
Associations
Accumulation in
- liver
- skin
- pancreas
- heart
- endocrine organs
- joints
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