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Cryptococcus Neoformans

• yeast-like fungus
• appears to be spread by birds
  • pigeon-droppings

History

• pulmonary symptoms uncommon
• Meningitis

Examination

• chest
  • lung cavitation
  • hilar lymphadeonpathy
  • pleural effusions
  • pulmonary fibrosis

Diagnosis

• staining and microscopy of tissue samples
• latex agglutination test

Treatment

• Amphotericin (0.3-0.5mg/kg IV) 3 months
• +/- flucytosine (100-200mg/kg)
• fluconazole