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Anion Exchange Resins
Drugs in class
- cholestyramine
- colestipol
Uses
Mechanism of Action
- bind bile acids
- inhibit reabsorption of bile salts and cholesterol
- greater proportion of cholesterol synthesised in liver is converted to
bile salts
- reduced absorption of cholesterol
Side Effects
- unpalatable / QDS delivery
- constipation
- abdominal discomfort
- decreased absorption of fat-soluble vitamins
Contra-indications
- complete biliary obstruction
Interactions
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