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ACE inhibitors

• angiotension-converting enzyme inhibitors

Use

• Reduce blood pressure
• prolong survival after Myocardial Infarction (SAVE trial)
• Heart Failure (CONSENSUS, SOLVD trials)

Contra-indications

• pregnancy
• renal arterty stenosis

Drugs in class

• captopril
• ramipril
• enalapril

Side Effects

• decline in renal function
• acute hepatitis (enalapril)
• cough
• hyperkalaemia