Drugs Used In Diabetes Mellitus

[ Home ] [ Up ]

Pages Below:

Drugs Used In Diabetes Mellitus

Insulin Replacement

Sulphonylureas

Repaglinide

Biguanides

Thiazolidinediones

Acarbose

Type I

• Insulin

Type II DM (Insulin deficiency and beta-cell defect)

• Stimulate pancreatic insulin release
  • sulphonylureas
  • repaglinide
• Increase insulin sensitivity  
  • biguanides (=metformin)
  • thiazoloidinediones
• Interfere with nutrient absorption
  • acarbose

Step-up policy treatment (NICE guidelines)

1. Diet and exercise alone
2. Metformin and sulphonylurea monotherapy
3. Metformin and sulphonylurea combination therapy
4. Insulin or Rosiglitazone and metformin (preferred esp. if obese)
5. Rosiglitazone and sulphonylurea (if metformin intolerant)

[ Home ] [ Up ]