Lamivudine

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Lamivudine


  • antiviral drug
  • Nucleoside analogue - branch chain terminator.

Indications

Use

  • Very effective at low HBV DNA states.
  • Dose – 100mg OD. Life long therapy. Expensive.
  • LFTs every 3mths. Test serological markers every 6mths.
  • Life threatening lactic acidosis and hepatomegaly with liver disease.

Side Effects

  • diarrhoea
  • cough
  • headache
  • alopecia
  • muscle disorders
  • nasal symptoms
 

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