Low Molecular Weight Heparins

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Low Molecular Weight Heparins


  • Like heparin
  • probably better
    • do not need monitoring
    • one daily injection

Drugs in class

  • dalteparin 
  • enoxaparin 
  • tinzaparin

Mechanism of action

  • bind to antithrombin III
  • activated antithrombin III now forms a complex with the factor Xa 
  • prevents Xa from converting prothrombin to thrombin (i.e. there is no thrombin formation)
  • further thrombus formation prevented     
 

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