Muscarinic Antagonists

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Muscarinic Antagonists

Drugs in class

• hyoscine

• ipratropium

• oxybutinin
• propantheline
  • many anti-muscarinic side effects
• Tricyclic Antidepressants

Mechanism of action

• inhibit vagally mediated bronchoconstriction

Uses

• ipratropium

  • mainly used for Chronic Obstructive Airways Disease

  • also tried in Asthma

• detrusor instability

Side effects

• dry mouth

• prostatic symptoms

• glaucoma

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