Nystatin

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Nystatin


  • antifungal antibiotic

Mechanism of Action

  • increases membrane permeability by creating a membrane pore with a hydrophilic centre
  • leakage and loss of small molecules
  • higher affintity for ergosterol than cholesterol

Pharmacokinetics

  • little or none absorbed systemically

Route

  • suppositories (vaginitis)
  • oral suspension

Resistance

  • does not develop during therapy
 

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