Hepatitis E

• single-stranded RNA calicivirus

• excreted in faeces, spread by faecal-oral route

• waterborne infection in India

Symptoms

• incubation period is 6-8 months

• generally mild

• severe in pregnant women (up to 20% mortality)

  • DIC in third trimester

Hep E

• Spread: enterally
• No carrier state, no progress to chronic liver disease

 No treatment or vaccine. Self limiting. Avoidance (good sanitation, hygiene)

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