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Large Intestine Histology
No plicae circulares or villi present. Outer muscular layer
divided into three equally spaced bands
- mucosa
- epithelium
- numerous crypts of Lieberkühn
- principal function in absorption of water and electrolytes
- goblet cells increase nearer to rectum
- all epithelial cells arise from precursors at base of crypts
- cells shed after 6 days for absorptive and goblet cells (4 weeks
for enteroendocrine cells)
- submucosa
- muscularis externa
- outer muscle layer divided into 3 longitudinal bands - teniae coli
- formation of haustration in wall
- peristalsis normally occurs once a day in order to empty distal colon
- serosa
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