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- can be part of MEN I
- produced by gastrinoma
- arises from G cell of pancreas
- secretes large amounts of gastrin
- maximal gastric acid secretion produced
- produces Peptic Ulcer Disease in
- large deep ulcers, sometime multiple
- diarrhoea results from low pH of gut contents
- jejunal mucosal abnormalities seen
- diagnosis confirmed by high serum gastrin
Treatment
Prognosis
- death due to malignancy of tumour
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