Pages Below:
Skin Immunology Skin Infections
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- Functions
- Mechanical Protection
- keratin
- thickness
- melanin against UV
- micro-organisms
- Permeability barrier
- water and electrolytes
- lipids between epidermal cells
- keratin
- (oil soluble substances can enter anyway)
- Sensory Perception
- pain
- touch
- vibration
- temperature
- Thermoregulation
- Evaporation
- surface radiation
- hence capillary loops
- Immunological barrier
- keratin as antigen barrier
- Langerhans cells
- T lymphocytes
- Three layers:
- Appendages
- Hair Follicles
- Skin Glands:
- Nails
- Made of hard keratin
- grow at 1/2 mm per week
- finger nails grow 4x as fast as toes
- Seruminous gland
- External auditory meatus
- Produces ear wax
- Thick Skin:
- No Hair
- Thick stratum corneum
- Deeper dermal papillae and epidermal pegs give improved resistance to abrasion
- Found on palm, sole of foot
- Thin Skin
- Hairy
- Fairly smooth dermo-epidermal junction
- dermal papillae
- epidermal pegs
5.5 SKIN [Hist]
[Currently: 1 lecture + 1 ´ 2h class]
Functions. |
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Epidermis: cell types; epidermal layers; growth and
differentiation (stem cells). Skin appendages: hair, nails. |
Dermatology: retinoids and epidermal cancers, psoriasis,
acne. Teratogenic side effects |
Nerve endings of skin; sweat glands (eccrine/merocrine and
apocrine). |
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Blood supply of skin. |
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