Pyrexia of Unknown Origin

Definition

1. temp >38^oC

2. for >2 weeks

3. for which there is no known cause

Causes

• Infection

• malignancy

• connective tissue disorders

• antibiotics

• factitious

Infectious Causes

• tuberculosis (25-20%)

• abdominal sepsis

  • cholecystitis

  • pyelonephritis

  • liver abscess

• pelvic sepsis

• dental abscess

• rheumatic fever

• osteomyelitis

• HIV

• endocarditis

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