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Myelodysplasia
- defect in stem cells
- abnormalities of all three myeloid cell lines
- transformation to acute leukaemia in 30%
Types
- refractory anaemia (RA)
- refractory anaemia with ringed sideroblasts (RARS)
- refractory anaemia with excess of blasts (RAEB)
- refractory anaemia with excess of blasts in transformation (RAEB-T)
- chronic myelomoncytic leukaemia (CMML)
Treatment
- supportive care
- 'Gentle' chemotherapy
- Intensive Chemotherapy
- Bone Marrow Transplantation
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