Severe Combined Immunodeficiency

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Severe Combined Immunodeficiency (SCID)


  • X-linked variant due to failure of common gamma chain (IL-2, IL-4, IL-7, IL-11, IL-15 receptors)
  • Adenosine deaminase deficiency
  • Purine nucleoside phosphorylase deficiency
  • bare lymphocyte syndrome (lack of MHC-II)
 

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