Subacute Combined Degeneration of the Cord

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Subacute Combined Degeneration of the Cord

History

• tingling in feet (more than hands)

• difficulty in gait

• visual disturbances

• psychiatric disturbances

Examination

• observation

  • patient in 60s

  • fair hair

  • blue eyes

  • pale

    • due to macrocytic anaemia

Cause

• Vitamin B₁₂ deficiency

Pathology

• demyelination of white matter in cord and peripheral nerves

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