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Histology of Pancreas

endocrine and exocrine components

Endocrine component

secretes insulin and glucagon into blood
islets of Langerhans within exocrine tissue
a-cells
- secrete glucagon
b-cells
- secret insulin
d-cells
- secrete somatostatin
bountiful capillary network within islets of Langerhans
blood reaching b- cells has always passed a- and d-cells

Exocrine component

secretes digestive enzymes into duodenum
serous gland resembles parotid gland
tubuloacinar structure of glands
acinar cells involved in
- secreting low volume enzyme rich fluid -
  - trypsinogen, pepsinogen, procarboxypeptidase
  - amylase
  - lipase
  - deoxyribonuclease, ribonuclease
- extensive Golgi and rER
- basal nucleus
duct cells
- large volume of bicarbonate rich fluid

9.2.2.5 Histology of Salivary Glands and Pancreas [Hist]

Microscopical anatomy of the salivary glands and pancreas in relation the secretion of saliva and pancreatic juice

(With 1.5, currently 1 lecture and 1x2h class)

Salivary glands: parotid, submandibular; sublingual glands; myo-epithelial cells, serous cells, mucous cells; control of secretion.
Exocrine pancreas: acini and ducts; cell biology and control of synthesis and secretion of zymogen granules.	Pancreatitis