- Produced by two types of specialised glial cells
- Increass rate of conduction
- current flow restricted to regularly spaced bare patches called Nodes of Ranvier
- Comprises a phospholipid bil;ayer containing specific myelin membrane proteins
- Major myelin group of genes comprises three genes encoding protein zero (P0),
myelin basic protein (MBP) and proteolipid protein (PLP)
- They possess adhesive properties
- Defective function of myelin leads to disease.
- Shiverer mouse has defect in MBP gene
- Autoimmune attack of myelin sheath can lead to demyelination (often aimed at MBP)
this can lead to multiple sclerosis
6.4 MYELINATION [Neuro]
| Measurement of whole-nerve conduction velocity. |
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| Differences between CNS and PNS. |
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| Demyelinating diseases: Multiple sclerosis. * |
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| Conduction block. |
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