- secreted in response to glucose deficiency
- stimulated by amino acid arginine and alanine, aided by
gastric released secretagogues
- vagal stimulation (acetylcholine) increase glucagon
releaser
- somatostatin inhibits release
- binds to membrane bound receptor, raises cAMP
- increases glycogenolysis and decreases glycolysis
- stimulates gluconeogenesis
14.5.2 Glucagon
| actions in liver to maintain plasma levels of metabolic
substrates |
somatostatin, pancreatic polypeptide |
| synergism of actions with catecholamines, glucocorticoids,
growth hormone |
|
|