Luteinising Hormone
(LH)
- In Testis:
- induces Leydig cells
to produce testosterone
- In Ovaries:
- a surge of LH (in co-op. with FSH) at midcycle induces ovulation
- maintains the corpus luteum after ovulation
- induces luteal cells to produce progesterone
- Control of release is via hypothalamic GnRH (pulsatile), and modulated by
feedback loops involving the ovarian or testicular steroids
14.2.3.5 LH = luteinising hormone; FSH = follicle-stimulating hormone (from
gonadotroph cells)
| actions on ovary in female; on testis in male |
|
| control: via pulses of hypothalamic GnRH; feedback of
gonadal hormones |
|
| dysfunctions: hypogonadism, precocious puberty,
infertility. |
|
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