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- released from duodenum and upper jejunum when stimulated by presence of
acid
- causes extralobular secretion of bicarbonate rich aqueous component of
pancreatic juice
- inhibits gastrin secretion by G cells
- decreases response of parietal cells to secretagogues (acetylcholine,
gastrin, histamine, etc.)
- stimulates chief cells to produce pepsinogen
14.6.3 Secretin
| produced from duodenum to ileum |
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| actions: stimulation of HCO3 secretion from
pancreas and liver |
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| stimuli for secretion: acid in duodenum |
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