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Schistosomiasis

Species

• Schistosoma mansoni
• Schistosoma japonica
• Schistosoma haematobium
  • responsible for bladder disease

Course

• enters through skin
• migrates through portal veins to reside in liver
• eggs migrate through tissues to pass through gut and bladder wall
• damage caused by immune reaction to eggs

Complications

S. Haematobium

• ulcers
• papillomata
• cysts
• giant granulomata
• sever bladder contracture
• risk of bladder cancer (squamous carcinoma) in long-standing infection