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Delayed Puberty
Causes
Constitutional delay
Low Gonadotrophins
- systemic disease
- cystic fibrosis
- severe asthma
- Crohn's disease
- organ failure
- anorexia nervosa
- starvation
- excess physical training
- Hypothalamopituitary disorders
- panhypopituitarism
- isolated gonadotrophin / growth hormone deficiency
- intracranial tumours
- Kallman's syndrome
- Acquired hypothyroidism
High Gonadotrophins
- chromosomal abnormalities
- Klinefelter's syndrome
- Turner's syndrome
- steroid hormone enzyme deficiencies
- Acquired gonadal damage
- post-surgery
- chemotherapy
- radiotherapy
- trauma
- torsion of the testis
- autoimmune disorder
Treatment
- identify and treat underlying pathology
- ensure normal psychological adaptation
- accelerate growth and promote entry into puberty
Males
Females
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