Adrenaline

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Adrenaline

• See Adrenaline

Effects

• a-receptors cause
  • vasoconstriction
  • iris dilation
  • intestinal relaxation
  • intestinal sphincter contraction
  • pilomotor contraction
  • bladder sphincter contraction
• b₁ receptors cause
  • cardioacceleration
  • increased myocardial strength
  • lipolysis
• b₂ receptors cause
  • vasodilation
  • intestinal relaxation
  • uterus relaxation
  • bronchodilation
  • calorigenesis
  • glycogenolysis
  • bladder wall relaxation

Use

• Cardiac Arrest
  • 10ml 1:10,000
• Anaphylaxis
  • 5ml 1:10,000 / 0.5ml 1:1000 IM
• Croup
  • nebulised 1:1000
• Chronic Glaucoma
  • NOT Closed angle Glaucoma
• Local Anaesthesia

Cautions

• heart disease
• Diabetes Mellitus
• Hyperthyroidism
• Hypertension
• cerebrovascular disease
• Closed angle Glaucoma
• 2nd stage of labour

Side-Effects

• anxiety
• tremor
• tachycardia
• cold extremities
• arrhythmias
• cerebral haemorrhage
• pulmonary oedema
• nausea
• vomiting
• sweating
• weakness
• dizziness
• hyperglycaemia

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