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Allopurinol
- xanthine oxidase inhibitor
Use
- treatment of Gout
- prevention of tumour lysis syndrome
Cautions
- due not use until one month after acute attack of gout
- ensure adequate fluid intake
Side Effects
- hypersensitivity
- rash
- exfoliation
- fever
- lymphadenopathy
- arthralgia
- eosinophila
- Stevens-Johnson
- vasculitis
- hepatitis
- renal impairment
- seizures
- GI disturbance
- malaise
- headache
- vertigo
- drowsiness
- visual disturbance
- hypertension
- alopecia
- hepatotoxicity
- paraesthesia
- neuropathy
- gynaecomastia
- blood disorders
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