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Dinoprostone
- prostaglandin E2
analogue
- uterus more sensitive to dinoprostone than oxytocin in 2nd trimester
Use
- induction of labour in 2nd trimester (late therapeutic abortion)
- induction and augmentation of labour
- oxytocin preferred due to prostaglandin side effects
Route
- extra amniotic instillation or 3mg vaginal tablets/pessary / gel (2nd dose
6-8 hours later if necessary)
Adverse Effects
- diarrhoea
- flushing
- headache
- hypotension
- fever
- nausea
- vomiting
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