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Lamivudine
- antiviral drug
- Nucleoside analogue - branch chain terminator.
Indications
Use
- Very effective at low HBV DNA states.
- Dose – 100mg OD. Life long therapy. Expensive.
- LFTs every 3mths. Test serological markers every 6mths.
- Life threatening lactic acidosis and hepatomegaly with liver disease.
Side Effects
- diarrhoea
- cough
- headache
- alopecia
- muscle disorders
- nasal symptoms
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