Antidepressants

[ Home ] [ Up ]

Pages Below:

Selective Serotonin Reuptake Inhibitors
Tricyclic Antidepressants
Monoamine Oxidase Inhibitors

Antidepressants

• amitryptylline
• dotheipin
• imipramine
• lofepramine

• citalopram
• fluvoxamine
• fluoxetine
• paroxetine
• sertraline
• nefazadone

• phenelzine
• tranylcypromine

• venlafaxine

• reboxetine

• mirtazapine

• mianserin
• trazodone
• maprotiline

• moclobemide

Mechanism of action

• block reuptake of noradrenaline / serotonin
• ? modulates pre-/post- synaptic receptors

Administration

• oral
• effect not usually apparent <2 weeks (max 6 weeks)

Indications

• depressive illness & prevention of relapse
• phobic anxiety
• obsessive compulsive neurosis

 Side effects

• anticholinergic
• antiadrenergic
• overdose
  • fatal cardiac arrythmias
  • seizures
• SSRIs
  • nausea
  • anorexia
  • headache
• MOAIs
  • the "cheese effect"

[ Home ] [ Up ]