Thiazide diuretics

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Thiazide diuretics


  • act on distal convoluted tubule
  • inhibit sodium reabsorption

Drugs in class

  • bendrofluazide
  • chlorthalidone
    • longer duration of action
    • used if risk of urinary retention
  • indapamide

Use

Side effects

  • postural hypotension
  • impotence
  • mild GI disturbance
  • impaired glucose tolerance
  • hyperuricaemia
  • hyponatraemia
  • hypokalaemia
  • hypomagnesaemia
  • allergy

Interactions

 

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