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Vigabatrin
Indications
- Epilepsy
- All types
- effective in patients resistant to other drugs
Mechanism of action and pharmacology
- Inhibits GABA transaminase
- 1g daily in single or two divided doses
- increased according to response
Adverse effects
- Common ones include
- drowsiness
- irritability
- confusion
- weight gain
- Psychotic reactions including
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