Drug Induced Lupus

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Drug Induced Lupus

Drugs

• procainamide

• hydralazine

• isoniazid

• anticonvulsants

• chlorpromazine

Rare

• penicillin

• penicillamine

• sulphonamides

• sulphasalzine

• oral contraceptives

• minocycline

• anti-TNF alpha drugs

Symptoms

• commonly

  • polyarthritis

  • rash

  • pleurisy/ pericarditis

  • pulmonary infiltrates

  • positive ANA

  • resolution when drug stops

• Rare

  • renal

  • psychiatric disease

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