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Rheumatoid Factor
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IgM against IgG
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15%-20% normal population (5% 60-70, 10-25% >70)
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Not raised in 20-35% RA
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Best ordered when high clinical suspicion RA or
cryoglobulinaemia
Occurs in
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CHronic disease
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hepatic
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pulmonary disease
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Rheumatoid
arthritis
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Other rheumatic diseases
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SLE
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Systemic sclerosis
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Sjogrens
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Polymyositis
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Neoplasms
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Infections
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viral, parasitic, bacterial - TB, leprosy
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subacute bacterial endocarditis
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Cryoglobulinaemia
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