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Cardiac Enzymes
- Measured after Myocardial Infarction
- necrosis of cardiac muscle releases enzymes into circulation
- serial measurements
Creatinine Kinase
- peaks within 24 hours
- usually back to normal in 48 hours
- sources
- heart muscle
- brain
- skeletal muscle
- different isoenzymes exist
- CK-MB specific to heart muscle
Troponin I / Troponin T
- released early
- persist for up to seven days
- highly specific for cardiac injury
Aspartate aminotransferase / Lactate dehydrogenase
- non-specific
- rarely used
- LDH
- peaks at 3-4 days
- remains elevated for up to 10 days
- useful in confirming MI days after chest pain
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