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Mitral valve prolapse
 
  - mid-late systolic murmur
 
  - only murmur that changes with posture
    
      - earlier on standing
 
      - later on lying
 
     
   
 
Complications
  - endocarditis
 
  - rupture
 
  - arrhythmias
 
 
Prognosis
  - regression - 11%
    
      - can regress with large reduction in afterload / BP
 
     
   
  - progression -51%
    
      - predictive of progression
 
     
   
  - asymptomatic are stable
 
  - symptomatic 5 year survival 50-60%
 
 
Signs
  - Left atrium and left ventricular dilatation (shifted apex)
 
  - Pansystolic murmur
 
 
Management
Medical
  - vasodilators
    
      - nifedipine
 
      - ACE-inhibitors
 
     
   
 
Surgical
  - mitral valve repair / replacement
 
 
 
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