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Asbestosis
- asbestos fibres 5-100mm x 0.25-0.5mm
- go deep into alveoli
- macrophages ingest fibres and die
History
Examination
- finger clubbing
- late inspiratory crackles
- lower lobes more severely affected
Pathology
- diffuse pulmonary fibrosis leads to honeycomb lung
Complications
- adenocarcinoma (about 20 years after exposure)
- mesothelioma (about 30 years after exposure)
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