Cartilage

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Cartilage


  • Can become calcified and eventually turns to bone.

Types

  • hyaline:
    • matrix contains 40% (dry weight) collagen
    • Mainly type II collagen, thinner than type I
    • cells (chondrocytes) in individual lacunae
    • fibres increase in diameter from lacunae into matrix
    • proteoglycans
    • present in high concentrations and form firm gel
    • principal proteoglycans are keratan sulfate and chondroitin sulfate
  • fibrocartilage
    • closely resembles dense regular connective tissue
    • found at insertion of ligaments and tendons and on rim of intervertebral discs
    • cell in lacunae have thin capsules
    • chondrocytes in small amount of cartilage matrix in rows between parallel collagen type I fibres
  • elastic
    • e.g. external ear
    • more opaque and yellowish in colour
    • less abundant matrix
    • much of matrix is elastin fibres
    • develop from areas of primitive connective tissue

 

(a) Cartilage. Cells: chondroblasts, chondrocytes. Matrix of hyaline cartilage: proteoglycan aggregates / type II collagen (plus elastin in elastic cartilage; type I collagen in fibrocartilage).
 

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