Histology of Oesophagus


  • non-keratinised stratified squamous epithelium
  • submucosa forms a number of longitudinal folds which flatten as a bolus of food passes
  • in upper third muscularis externa is striated muscle
  • in midddle third muscularis externa is mix of striated and smooth muscle
  • in lower third muscularis externa is smooth muscle
    • postganglionic neurons are in wall of oesophagus
  • surrounded by adventitia in thorax, short length in abdomen covered in serosa
  • oesophageal glands
    • tubuloalveolar,
    • concentrated in upper half,
    • produce slightly acid mucus
    • lubricates passage of food
  • oeophageal cardiac glands
    • terminal part of oesophagus
    • neutral mucus protects against acid reflux