Menstrual Cycle

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  • Begins with first day of menstruation
  • menstruation caused by fall in luteal oestrogen, progesterone and inhibin leading to rise in FSH and LH a day or so later.
  • Antral growth proceeds
  • Oestrogen, androgens and inhibin rise,  FSH falls, LH flattens
  • Dominant follicle selection leads to oestrogen rise and surge, positive feedback leads to surge in FSH and LH
  • Ovulation
  • Oestrogen, androgen, inhibin levels fall, progesterone rises.
  • FSH, LH levels drop through lack of positive feedback
  • Progesterone levels continue to rise depressing gonadotrophin levels.
  • At luteolysis progesterone, oestrogen, etc. levels fall and negative feedback effects on LH and FSH removed.
  • Endometrial sloughing
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