similar rates throughout year but proportionally more in summer due to fewer numbers of strep pneumoniae / viral pneumonia
most common 5-15 (school-age)
epidemic disease 4-8 years
strict aerobe
passes through 0.45 µm filter
worldwide incidence
no seasonal variation
Primarily 5-15 years
trasmission by aerosolised droplet
strict human pathogen
upper respiratory tract infections
2-3 weeks after exposure
low-grade fever, malaise headache
dry, non-productive cough
lower respiratory tract infections
tracheobronchitis
bronchopneumonia
atypical
patchy
otitis media
erythema multiforme (Stevens-Johnson syndrome)
haemolytic anaemia
myocarditis
pericarditis
neurologic abnormalities
difficult
2-6 weeks for culture
complement fixation test available
Erythromycin drug of choice
tetracycline can be used in older children/adults
will not be immune to reinfection