Progesterone


  • Causes endometrial secretion
  • Raises basal body temperature
  • aldosterone inhibition causes water and sodium retention
  • Enhance negative feedback effects of oestradiol and so cause reduced release on LH and FSH
  • Remove positive feedback effects of oestradiol and so inhibits surges of FSH and LH
  • Acts primarily to reduce GnRH pulse frequency in hypothalamus
  • levels rise shortly after ovulation
    • decreases cervical mucus and transforms to a thick, nonelastic state

Pharmacology

 

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